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Figure 5 | Journal of Biomedical Science

Figure 5

From: Green tea extract supplement reduces D-galactosamine-induced acute liver injury by inhibition of apoptotic and proinflammatory signaling

Figure 5

A: Green tea (GT) extracts inhibit the mitochondrial apoptosis-signaling pathway. The cytosolic and mitochondrial fractions were prepared at 6 hr after D-GalN from the livers and subjected to western blot analysis for Bax and cytochrome c (Cyt c), respectively. Note that GT treatment decreased the D-GalN-induced cytosolic Bax translocation to mitochondria and accumulation of Cyt c in the cytosol. B: Low dose (LGT) and high dose (HGT) of GT decreased D-GalN enhanced proapoptotic Bax/Bcl-2 ratio, CPP32 and PARP expression, and lipogenic enzyme (SREBP-1) in the liver subjected to 1–3 days of D-GalN intoxication.

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Journal of Biomedical Science

ISSN: 1423-0127