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Table 1 Modulation of expression and secretion of molecules by LPLI

From: Molecular mechanisms of cell proliferation induced by low power laser irradiation

Classification Molecules Biological effects of LPLI
Growth factors BDNF, GDNF, bFGF, IGF-I,
KGF, PDGF, TGF-β, VEGF
Proliferation, Differentiation,
Bone nodule formation
Interleukins IL-1α, IL-6, IL-8, IL-2, IL-4 Proliferation, Migration, Immunological activation
Inflammatory cytokines PGE2, COX-2, IL-1β, TNF-α Inhibition of inflammation
Small molecules ATP, cGMP, ROS, Ca2+, NO Normalization of cell function,
Pain relief, Healing, Mediating cell activities, Migration, Angiogenesis