Figure 5

Histology and morophometry of atherosclerotic lesions. Photomicrographs of light microscopy of representative sections of the coronary artery tissues from p21^-/- and wild type mice. Magnification is ×20 for all tissues. Haematoxylin and eosin staining of in the coronary artery issues of wild type mice fed with regular diet (a), high fat diet (b); p21^-/- mice fed with regular diet (c) and high fat diet (d) is shown. Black arrows indicate areas with scar. The graph (B) shows the mean lesion area (values are Mean ± SEM) per mouse. *p < 0.01, high fat diet (HFD) vs regular diet (RGD), wild type mice and **p < 0.0001, high fat diet vs regular diet in p21^-/- mice.