Table 3 Summary of the pre-S genotyping results by DNA sequencing and Pre-S Gene Chip analysis in 20 HBV carriers.
Case | DNA Sequencing Result | Pre-S Gene Chip Result |
|---|---|---|
1 | wild-type | wild-type |
2 | 1. wild-type | 1. wild-type |
| Â | 2. del nt 2894 to 3100 | 2. del nt 2894 to 3013 and nt 3074 to 3103 |
3 | wild-type | wild-type |
4 | wild-type | wild-type |
5 | 1. wild-type | 1. wild-type |
| Â | 2. del nt 3040 to 3111 | 2. del nt 3044 to 3103 |
6 | wild-type | wild-type |
7 | del nt 3218 to 8 | wild-type |
8 | 1. wild-type | 1. wild-type |
| Â | 2. del nt 3084 to 3188 | 2. del nt 3074 to 3103 and nt 3134 to 3193 |
| Â | 3. del nt 3148 to 29 | 3. del nt 3134 to 32 |
| Â | 4. del nt 3138 to 59 | 4. del nt 3134 to 62 |
9 | 1. wild-type | 1. wild-type |
| Â | 2. del nt 3202 to 36 | 2. del nt 3194 to 32 |
10 | del nt. 2913 to 3118 and nt 3217 to 9 | del nt 2924 to 2983 and nt 3014 to 3103 |
11 | Wild-type | wild-type |
12 | wild-type | wild-type |
13 | 1. wild-type | 1. wild-type |
| Â | 2. del nt 3022 to 3205 | 2. del nt 3014 to 3103 and nt 3134 to 2 |
| Â | 3. del nt 3132 to 37 | 3. del nt 3134 to 32 |
| Â | 4. del nt 3057 to 3198 | 4. del nt 3074 to 3103 and nt 3134 to 3193 |
| Â | 5. del nt 3132 to 3182 | 5. del nt 3134 to 3193 |
14 | del nt 2854 to 2871 | del nt 2854 to 2878 |
15 | 1. del nt 3205 to 3213 | 1. wild-type |
| Â | 2. del nt 34 to 54 | 2. del nt 33 to 62 |
16 | 1. wild-type | 1. wild-type |
| Â | 2. del nt 3041 to 3126 | 2. del nt 3044 to 3103 |
| Â | 3. del nt 25 to 56 | 3. del nt 33 to 62 |
17 | 1. wild-type | 1. wild-type |
| Â | 2. del nt 2984 to 3221 | 2. del nt 2984 to 3013, nt 3044 to 3103, and nt 3134 to 2 |
18 | 1. wild-type | 1. wild-type |
| Â | 2. del nt 3 to 56 | 2. del nt 3 to 62 |
19 | del nt 3040 to 3111 | del nt. 3044 to 3103 |
20 | del nt 2948 to 3097 and nt 3112 to 2 | del nt 2954 to 3013, nt 3044 to 3103, and nt 3194 to 2 |
Pre-S mutant Clones ( n ) | 21 | 19 |
Cases with Pre-S Mutations ( n ) (%) | 14 (70%) | 13 (65%) |