Figure 5

Effect of 5-FU-mediated hematopoietic growth factor gene therapy on tumor size. By day 25, tumor volumes were 1422.61 ± 320.32 mm³ (HFCL + 5-FU) and 1282.35 ± 451.15 mm³ (HFCL/EF + 5-FU), and the tumor inhibitory rates were 46.20% and 51.51%, respectively. The tumor volumes in the HFCL + NS and HFCL/EF + NS group increased from 0 to 25 days, reaching volumes of 2644.43 ± 466.12 mm³ and 2480.54 ± 688.24 mm³, respectively. The corresponding inhibitory rates were 0.00 and 0.06%, respectively.