Figure 2

Effect of puerarin in middle cerebral artery occlusion (MCAO)-induced regional cerebral blood flow (rCBF) and neurobehavioral deficits in rats. (A) rCBF of solvent- and puerarin (50 mg/kg)-treated rats were measured by laser Doppler flowmeter in the MCA-supplied cortex. The value of rCBF were recorded every 10 min after MCAO and reperfusion periods. Each point (○, solvent-treated group; △, puerarin 50 mg/kg-treated group) and vertical bar represent the means ± S.E.M. (n = 6). (B) Neurobehavioral scores of solvent- and puerarin (50 mg/kg)-treated rats were recorded at 1 and 24 h after MCAO. Each point (○, solvent-treated group; △, puerarin 50 mg/kg-treated group) and vertical bar represent the means ± S.E.M. (n = 5).