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Figure 7 | Journal of Biomedical Science

Figure 7

From: Cyclic stretch enhances the expression of Toll-like Receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-κB pathway

Figure 7

Cyclic stretch increases TLR4 promoter activity. Upper panel, constructs of TLR4 promoter gene. Lower panel, quantitative analysis of TLR4 promoter activity. Cardiomyocytes were transiently transfected with pTLR4-Luc by gene gun. The luciferase activity in cell lysates was measured and was normalized with renilla activity (n = 3 per group). *P < 0.001 vs. control. **P < 0.001 vs. 2 h.

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