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Figure 1 | Journal of Biomedical Science

Figure 1

From: Sodium valproate-induced congenital cardiac abnormalities in mice are associated with the inhibition of histone deacetylase

Figure 1

Dose-dependent cardiac abnormalities in fetal mice prenatally exposed to NaVP. Cardiac abnormality rate increased significantly in fetal mice (gestation day 19) after prenatal exposure to NaVP (pregnant female mice received a one-time injection of NaVP on gestation day 7 at various doses). The cardiac abnormality caused by NaVP shows a dose-dependent pattern with the highest rate in the group of a treatment dose at 700 mg/kg body weight. * P < 0.05 vs. control without sodium valproate treatment.

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Journal of Biomedical Science

ISSN: 1423-0127