Figure 5
From: Nitroprusside modulates pulmonary vein arrhythmogenic activity
Effects of nitroprusside on the transient outward current (I to ) and sustained outward potassium currents (I Ksus ) in the PV cardiomyocytes (n = 6). Upper and lower panel shows the current tracings and I-V relationship of the Ito of before and after the administration of nitroprusside in PV cardiomyocytes. The Ito in the nitroprusside-treated PV cardiomyocytes was smaller than that in the control PV cardiomyocytes. Lower panel shows the current tracings and I-V relationship of the IKsus before and after the administration of nitroprusside in PV cardiomyocytes. The IKsus was larger in the nitroprusside-treated PV cardiomyocytes than that in the control PV cardiomyocytes. The insets of the current traces show the various clamp protocols. *P < 0.05, **P < 0.01, versus before nitroprusside PV cardiomyocytes.