Figure 5From: Characterization of Fabry mice treated with recombinant adeno-associated virus 2/8-mediated gene transferGb3 clearance from proximal renal tubules of kidney of rAAV 2/8-treated Fabry mice. (A) Wild-type mice, (B) Fabry mice (at 24 weeks), (C) 6 weeks after ERT, and (D) 6 weeks after gene therapy (2 × 1012 rAAV2/8-hAGA). The mice were killed 6 weeks after injection and kidney tissue was examined by electron microscopy. Gb3 containing myeloid bodies were recognized in proximal tubules (×8000).Back to article page