Figure 2From: Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin inhibits the proliferation of ARPE-19 cells17-AAG induces apoptosis in ARPE-19 cells. Following incubation with 3 μM 17-AAG for 24, 48 or 72 h, apoptosis was assessed using a flow cytometer to detect cells that were stained with Annexin V or PI, as described in the Methods section. Exposure to 17-AAG causes a significant population of ARPE-19 cells to proceed to a later stage of apoptosis.Back to article page