Figure 1

Effects of BFA on LNCaP cell growth. (A) Dose-dependent effects of BFA on LNCaP cell growth were assessed: after cells were cultured with 0-50 ng/ml of BFA for 72 h, those viable cell numbers were determined and expressed by the percent (%) relative to cell number in control (100%). (B) Effects of BFA on DHT-stimulated cell growth were examined: cells were grown with DHT (1 nM), BFA (30 ng/ml), or their combination for 72 h, and cell growth was assessed by the % of controls. All data are mean ± SD (standard deviation) from three separate experiments (*p < 0.05 compared with controls).