Figure 11

Photomicrographs of cells from BALF samples stained with Vectastain® Elite ABC kit. The animals received TAU (50 mg/kg/0.5 mL, i.p.) before (A-C) and after (D-F) LPS (0.02 mg). Cells from control (PBS pH 7.4) animals lacked TNFR1 positive cells (A and D). BALF from animals treated only with LPS (B and E) exhibited a modest increase in the number of TNFR1 positive macrophages relative to BALF from control (PBS pH 7.4) animals. A 3-day treatment with TAU, either before (C) or after (F) LPS, reduced the number of TNFR1 positive macrophages relative to BALF from animals receiving only LPS (magnification of 400x).