|
Pretreatment
|
[3H]Taurine uptake (% of control)
|
|---|
|
Compounds
|
TR-TBT 18d-1
|
TR-TBT 18d-2
|
|---|
|
Control
|
100 ± 7
|
100 ± 14
|
|
TNF- α 20 ng/mL
|
139 ± 11 *
|
150 ± 12 **
|
|
LPS 10 ng/mL
|
124 ± 4 **
|
128 ± 7 *
|
|
DEM 100 μM
|
137 ± 16 **
|
154 ± 11 **
|
|
H2O2 2 mM
|
85.2 ± 1.8 **
|
79.8 ± 3.2 **
|
|
SIN-1 1 mM
|
66.8 ± 2.2 **
|
84.2 ± 3.8 *
|
- Cells were treated with tumor necrosis factor-α (TNF- α, 20 ng/mL), lipopolysaccharide (LPS, 10 ng/mL), diethyl maleate (DEM, 100 μM), hydrogen peroxide (H2O2, 2 mM) and 3-morpholinosyndomine (SIN-1, 1 mM) for 24 hrs, respectively. [3H]Taurine (28 nM) uptake was performed at 37°C for 5 min. Each value represents the mean ± SEM (n=3-4). *p<0.05, ** p<0.01 significantly different from the control.
