Regulation of taurine transport at the blood-placental barrier by calcium ion, PKC activator and oxidative stress conditions

Table 2 Effect of oxidative stress inducing agents on [³H]taurine uptake in TR-TBT cells

Cells were treated with tumor necrosis factor-α (TNF- α, 20 ng/mL), lipopolysaccharide (LPS, 10 ng/mL), diethyl maleate (DEM, 100 μM), hydrogen peroxide (H₂O_2, 2 mM) and 3-morpholinosyndomine (SIN-1, 1 mM) for 24 hrs, respectively. [³H]Taurine (28 nM) uptake was performed at 37°C for 5 min. Each value represents the mean ± SEM (n=3-4). ^*p<0.05, ^** p<0.01 significantly different from the control.

ISSN: 1423-0127