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Figure 4 | Journal of Biomedical Science

Figure 4

From: Granulocyte-CSF induced inflammation-associated cardiac thrombosis in iron loading mouse heart and can be attenuated by statin therapy

Figure 4

G-CSF enhanced iron induced oxidative stress and leukocyte infiltration with aggravation of myeloperoxidase (MPO) activity in heart. (A and B) Immunoreactivity of 8-OHdG, 4-HNE (both are markers for oxidative stress) and CD45 (leukocyte marker) were compared and quantified between iron only (I) and I+G heart tissue. Representative results of three separate experiments are shown in (B). (C) MPO activities in heart tissue from all groups and their relative expression compared with actin were shown, *p < 0.01.

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Journal of Biomedical Science

ISSN: 1423-0127