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Table 1 GABA Content (μmoles/g wet wt.) in cerebellum and brain stem of Control and Experimental Groups of Neonatal Rats

From: Decreased GABAB receptor function in the cerebellum and brain stem of hypoxic neonatal rats: Role of glucose, oxygen and epinephrine resuscitation

Experimental groups

GABA Content (μmoles/g wet wt.)

Cerebellum

Brain stem

Control

6.45 ± 1.2

8.45 ± 1.8

Hx

2.02 ± 1.0a

4.06 ± 1.4a

Hx + G

6.25 ± 1.4 b

9.85 ± 2.2 b

Hx + G + O

6.60 ± 1.4 b

8.66 ± 1.4 b

Hx + O

3.55 ± 1.8 b

6.01 ± 1.5 b

Hx + E

3.05 ± 1.2 a

4.55 ± 1.6 a

Hx + G + E + O

3.12 ± 1.1 a

5.02 ± 1.4 a

  1. Values are Mean ± S.E.M of 4-6 separate experiments. Each group consist 6-8 rats.
  2. a p < 0.001 when compared to Control
  3. b p < 0.001, c p < 0.01 when compared to hypoxic group
  4. Hypoxic rats- Hx, Hypoxic rats glucose treated - Hx+G, Hypoxic rats oxygen treated - Hx+O, Hypoxic rats glucose and oxygen treated - Hx+G+O, Hypoxic rats epinephrine treated - Hx + E, Hypoxic rats glucose, epinephrine and oxygen treated - Hx+G+E+O