Fish-on-a-chip: a sensitive detection microfluidic system for alzheimer's disease

Table 1 List of biomarkers for Alzheimer disease and their sample source

Factor	Sample Source	Biomarkers	Ref
Histopathological factors	Urine, Blood	Amyloid beta peptide	[55, 56]
	CSF	Tau protein	[57]
	CSF	Phosphorylated tau	[58]
Genetic factor	Blood,saliva	APOE	[59, 60]
	CSF, blood,saliva	APP	[61, 62, 60]
	Blood	PS-1	[63]
	Blood	PS-2	[63]
Synaptic pathological factor	CSF	ADDL	[39]
Others	CSF	Somatostatin	[64]
	Blood	Metal ions	[65]

ISSN: 1423-0127