Table 1 The description of SNPs of arsenic-metabolized enzyme and the primers used for realtime PCR

GSTM1

Gene deletion

No protein

0.5749

5'-GAA CTC CCT GAA AAG CTA AAG C-3' & 5'-GTT GGG CTC AAA TAT ACG GTC G-3'

GSTT1

Gene deletion

No protein

0.4966

5'-TTC CTT ACT GGT CCT CAC ATC TC-3' & 5'-TCA CCG GAT CAT GGC CAG CA-3'

GSTP1

Exon 5

A→G

Ile105Val

(I105V)

0.2256

rs1695

5'-ACC CCA GGG CTC TAT GGG AA-3' & 5'-CAG GTT GTA GTC AGC GAA G-3'

GSTO1

Exon 4 C→A

Ala140Asp

(A140D)

0.1660

rs4925

C_11309430_30

GSTO1

Exon 4 -/AGG

Glu155del

(E155del)

0.0125

rs11509437

Forward: 5'-TCTAGGTGCCATCC TTG-3'

Reverse: 5'-TGATAGCTAGGAGAAATAA-3'

GSTO1

Exon 6 C→T

Glu208Lys

(K208E)

0.0125

rs11509438

C___11309432_20

GSTO1

Exon6 A→C

Thr217Asn

(T217N)

0.0000

rs15032

C___1174185_80

GSTO2

Exon2 5'UTR(-183)

A→G

---

0.2032

rs2297235

C___3223142_1_

GSTO2

Exon5 A→G

Asn142Asp

(N142D)

0.2467

rs156697

C___3223136_1_