Levels of p-Akt at 10 minutes after reperfusion (n = 8 each group). p-Akt levels were analyzed by western blot. PostC activated PI3K/Akt pathway. (A), PI3K inhibitor wortmannin reduced p-Akt levels after PostC. (B), JAK2 inhibitor AG490 reduced p-Akt levels after PostC. *p < 0.05 compared with I/R and PostC+Drug groups respectively.