Figure 2
From: Overexpression of Insig-1 protects β cell against glucolipotoxicity via SREBP-1c
Insig-1 increased cell viability and decreased cell apoptosis in the presence of high glucose induced glucolipotoxicity. INS-1 and INS-1-Insig-1 cells were stimulated with 11.2 and 25.0 mM glucose for 0, 24 and 72 h. A) Cell viability was measured by MTT assay, B) Cell apoptosis rates were detected by flow cytometric analysis. *P < 0.05; **P < 0.01 VS INS-1 cell at the same time point.