Effects of HDME (3~30 µmol/kg, p.o.) on airway resistance. Effects of HDME (3~30 µmol/kg, p.o.) on airway resistance (RL, A) and lung dynamic compliance (Cdyn, B) in sensitized and challenged mice which received aerosolized methacholine (MCh, 0.78~25 mg/ml) 2 days after primary allergen challenge. ### P < 0.001, compared to the non-challenged group. * p < 0.05, ** p < 0.01 and *** p < 0.001, compared to the control (vehicle) group. The number of mice in each group was 10. PBS, phosphate-buffered saline.