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Table 1 Scatchard analysis of [3H]GABA binding against GABA in the cerebral cortex of control and experimental rats

From: Decreased GABA receptor in the cerebral cortex of epileptic rats: effect of Bacopa monnieri and Bacoside-A

Group Bmax (fmoles/mg ptn) Kd (nM)
C 112.3 ± 6.3 2.6 ± 0.3
E 44.0 ± 3.5*** 1.5 ± 0.1**
E+B 89.8 ± 5.6@@ 2.3 ± 0.2
E+D 93.2 ± 4.7@@ 2.2 ± 02
E+C 80.7 ± 5.2@@ 2.1 ± 0.1
  1. Values are mean ± SEM of 4-6 separate experiments. Each group consist of 6-8 rats ** p < 0.01, *** p < 0.001 when compared to control, @@ < 0.01, @@@ < 0.001 when compared to epileptic group. C- Control, E- Epileptic, E+B- Epileptic rats treated with Bacopa monnieri, E+D- Epileptic rats treated with Bacoside A and E+C- Epileptic rats treated with Carbamazepine.