Table 2 Data on mRNA levels of osteoclast specific genes and RANK/RANKL/OPG genes in OP and OA

OSCAR

Osteoclast associated immunoglobulin-like receptor

0.574(0.345;0.854)

1.002(0.732;1.339)

0.54

0.002*

ITGB3

β₃ integrin

0.241(0.074;0.586)

0.285(0.143;0.994)

0.85

0.231

CTSK

Cathepsin K

0.288(0.121;1.109)

0.263(0.136;0.555)

1.10

0.786

ACP5

Tartrate resistant acid phosphatase (TRAP)

0.270(.128;1.011)

0.147(0.073;0.259)

1.84

0.049*

CALCR

Calcitonin receptor

0.223(0.138;0.644)

0.860(0.482;1.562)

0.26

< 0.0005**

TNFRSF11A

Receptor activator of nuclear factor κB (RANK)

1.580(0.687;3.939)

0.573(0.355;1.038)

2.76

0.002*

TNFSF11

Receptor activator of nuclear factor κB ligand (RANKL)

0.528(0.076;1.038)

0.091(0.027;0.253)

5.80

< 0.0005**

TNFRSF11B

Osteoprotegerin (OPG)

0.699(0.410;0.914)

0.776(0.308;1.615)

0.90

0.681

TNFSF11/TNFRSF11A

RANKL/RANK

0.241(0.083;0.928)

0.140(0.064;0.271)

1.72

0.076

TNFSF11/TNFRSF11B

RANKL/OPG

0.448(0.295;1.601)

0.112(0.075;0.193)

4.00

< 0.0005**