Figure 5

Immunohistochemistry of TRAIL stain in brains treated with AAV2/IL12 ( A, B ) or PBS ( C, D ), accompanied with tumor implantation; and that in the brain treated with nothing ( E ). Brain sections used in Figure 4 were also stained with hematoxylin for nuclei and TRAIL, and pictured as in Figure 4. TRAIL-positive cells show dark brown. The scale bars indicate 2 mm in 1^st and 2^nd columns and 100 μm in 3^rd and 6^th columns.