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Table 1 Changes in expression of genes affected by experimental treatments

From: Probiotic lactobacillus and estrogen effects on vaginal epithelial gene expression responses to Candida albicans

  Fold changes in mRNA expressionvs. control
Gene mRNA/Function Ca E2 Ca + E2 Pb Ca + E2 + Pb
ELK1/Inflammatory transcription factor + 2.49 - 3.06 + 1.59 - 4.46 + 1.09
Iκκα/Induces NF-κB nuclear translocation + 1.68 - 1.70 + 1.09 - 2.68 - 3.04
IL-1α/Inflammatory cytokine - 1.64 - 2.46 - 1.39 + 2.93 + 3.77
IL-1β/Inflammatory cytokine + 1.86 + 4.45 + 1.64 +36.18 + 3.80
IL-6/Inflammatory cytokine + 2.36 - 1.74 + 1.16 - 1.35 - 1.01
IL-8/Inflammatory cytokine + 1.24 - 3.99 + 2.59 + 10.70 - 1.02
TLR2/Inflammatory receptor for microbes + 1.10 - 1.39 - 2.33 - 1.22 - 3.37
TLR6/Inflammatory receptor for microbes - 1.09 - 5.64 - 1.93 - 2.94 - 5.08
TNFα/Inflammatory cytokine + 1.85 - 9.32 + 1.37 - 5.78 - 6.78
  1. Fold changes in mRNA expression were derived from the average values of real-time PCR threshold concentrations (n = 6, P < 0.05 by t-test) for each gene of interest compared to housekeeping genes. Abbreviations: (Ca) C. albicans, (E2) 17β-estradiol, (Pb) probiotic lactobacilli, an equal mixture of L. rhamnosus GR-1 and L. reuteri RC-14.
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Journal of Biomedical Science

ISSN: 1423-0127