Figure 1
From: Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells
Zerumbone induced GBM cell death . (A) U87MG and GBM 8401 cells were treated with DMSO or zerumbone at indicated concentrations for 24 h. Cell viability was then determined by the MTT assay. We used GBM8401 cells for further studies, since zerumbone had a greater effect on cell viability in GBM8401 cells. * p < 0.05, compared with the control group. (B) Cells were treated with DMSO, or zerumbone at indicated concentrations, for 24 h. After treatment, the percentage of sub-G0/G1 contentetric analysis of PI-stained cells as described in Materials and methods. Each column represents the mean ± S.E.M. of at least 3 independent experiments. * p < 0.05, compared with the control group.