Table 2 Compounds affected Sp1
From: Functional role of post-translational modifications of Sp1 in tumorigenesis
Drugs | Effect on Sp1 | Cancer type | Ref. |
|---|---|---|---|
Oldenlandia Diffusa (OD) | Positive | Breast cancer | [61] |
Arsenic trioxide | Negative | Bladder cancer | [62] |
Celecoxib | Negative | Pancreatic cancer | [63] |
Bortezomib | Negative | Acute myeloid leukemia | [64] |
Curcumin | Negative | Bladder cancer | [65] |
GT-094 | Negative | Colon cancer | [66] |
3,3′-diindolylmethane (DIM) | Positive | Breast cancer | [67] |
Indole-3-carbinol (I3C) | Negative | Breast cancer | [68] |
Trichostatin A (TSA) | Positive | Hepatoma | [69] |
Tolfenamic Acid | Negative | Pancreatic cancer | [70] |
Mithramycin A | Negative | ND | [71] |
Betulinic acid | Negative | Prostate and lung cancer |