Figure 6From: Mitofusion-2-mediated alleviation of insulin resistance in rats through reduction in lipid intermediate accumulation in skeletal muscleMFN2 overexpression lowered lipid intermediate accumulation in rat skeletal muscle, but had no significant effect on muscle TG accumulation. Rats were fed with high-fat diets for 8 weeks, and then were infected with Ad-Mfn2 (109 v.p./kg body weight) or empty Ad adenoviruses or PBS control for 3 weeks. The levels of TG (A), LCCoAs (B), DAG (C) and CER (D) were measured. *P < 0.05, **P <0.01, compared with Ad, n = 6.Back to article page