Skip to main content

Table 1 Quantitative histomorphometric assessment of nerve specimens 5-mm distal to crushed site of the sciatic nerve

From: Knockout of TLR4 and TLR2 impair the nerve regeneration by delayed demyelination but not remyelination

Group

n

Fiber count

Fiber width, μm

Fiber area, μm2

Total fiber area, μm2

Fiber debris area, μm2

Myelin area, μm2

Axon area, μm2

Axon width, μm

Sham

6

112 ± 13

5.25 ± 0.35

31.5 ± 3.1

3349 ± 260

23 ± 5*

16.1 ± 1.9

12.7 ± 1.9

3.19 ± 0.36

C57BL/6

5

106 ± 10

5.34 ± 0.16

31.8 ± 2.7

3235 ± 289

51 ± 16

16.0 ± 1.4

14.3 ± 1.6

3.61 ± 0.14

Tlr4−/−

6

56 ± 10*

4.14 ± 0.39*

19.6 ± 3.9*

1204 ± 392*

161 ± 24*

10.5 ± 2.1*

8.6 ± 1.8*

2.68 ± 0.28*

Tlr2−/−

6

46 ± 6*

4.16 ± 0.26*

19.6 ± 2.4*

943 ± 191*

178 ± 38*

10.8 ± 1.4*

8.1 ± 1.0*

2.61 ± 0.16*

  1. Data are shown as mean ± standard error (* indicated P < 0.05 compared with C57BL/6 group).
Back to article page

Journal of Biomedical Science

ISSN: 1423-0127