Table 1 miRNA targets that were significantly dysregulated in the whole blood and the grafted nerves by the miRNA array experiments in the untreated isograft, untreated allograft, and allograft with FK506 immunosuppression groups
From: Profiling circulating microRNA expression in a mouse model of nerve allotransplantation
Whole Blood | |||||
|---|---|---|---|---|---|
Allograft v.s. Sham operation | Allograft with FK506 v.s. Sham operation | Allograft with FK506 v.s. Allograft | |||
increased miRNA targets | log2 (ratio) | increased miRNA targets | log2 (ratio) | increased miRNA targets | log2 (ratio) |
No | Â | No | Â | miR-320 | 1.44 |
| Â | Â | Â | Â | miR-762 | 1.37 |
| Â | Â | Â | Â | miR-423-5p | 1.08 |
decreased miRNA targets | log2 (ratio) | decreased miRNA targets | log2 (ratio) | decreased miRNA targets | log2 (ratio) |
miR-720 | -1.75 | let-7d | -1.43 | No | Â |
miR-709 | -1.13 | miR-26a | -1.42 | Â | Â |
miR-2145 | -1.03 | let-7i | -1.44 | Â | Â |
miR-1195 | -1.01 | let-7a | -1.25 | Â | Â |
miR-690 | -1.01 | Â | Â | Â | Â |
Nerve grafts | |||||
Allograft v.s. Sham operation | Allograft with FK506 v.s. Sham operation | Allograft with FK506 v.s. Allograft | |||
increased miRNA targets | log2 (ratio) | increased miRNA targets | log2 (ratio) | increased miRNA targets | log2 (ratio) |
miR-125b-3p | 1.02 | No | Â | miR-125b-3p | 1.54 |
| Â | Â | Â | Â | miR-672 | 1.15 |
| Â | Â | Â | Â | miR-467b* | 1.03 |
decreased miRNA targets | log2 (ratio) | decreased miRNA targets | log2 (ratio) | decreased miRNA targets | log2 (ratio) |
No | Â | miR-2140 | -1.16 | No | Â |