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Table 5 Value of selected laboratory features in predicting a laboratory-positive diagnosis of dengue in suspected dengue patients during the 2007 outbreak in southern Taiwan

From: Clinical and laboratory predictive markers for acute dengue infection

Laboratory feature Dengue (+)* Dengue (−)* Sensitivity (%) Specificity (%) Positive predictive value (%) Negative predictive value (%)
(1) WBC <4000/cmm 315/376 53/114 83.8 53.5 85.6 50.0
(2) PLT < 150 × 103/cmm 314/376 52/114 83.5 54.4 85.8 50.0
(3) AST/ALT > 1.5 297/338 64/96 87.9 33.3 82.3 43.8
(4) CRP < 20 mg/L 335/357 75/102 93.8 26.5 81.7 55.1
(5) aPTT > 38 sec 227/301 37/80 75.4 53.8 86.0 36.8
(1) + (2) 276/376 52/114 73.4 45.6 84.1 34.2
(1) + (4) 291/357 34/102 81.5 66.7 89.5 50.7
(1) + (2) + (3) 228/338 38/96 67.5 60.4 85.7 34.5
(1) + (2) + (4) 255/357 27/102 71.4 73.5 90.4 42.4
(1) + (2) + (5) 209/301 26/80 69.4 67.5 88.9 37
(1) + (2) + (3) + (4) 221/338 26/96 65.4 72.9 89.5 37.4
(1) + (2) + (3) + (4) + (5) 172/301 11/80 49.5 86.3 93.1 31.2
  1. WBC: white blood cell, PLT: platelet, AST: aspartate aminotransferase, ALT: alanine aminotransferase, CRP: C-reactive protein, aPTT: activated partial thrombin time. *Numbers were presented as positive cases / examined case.