Figure 6

DPM is more pro-inflammatory than PAM after activated by Aβ, LPS, and IFN-γ. A. PAM and DPM were treated with vehicle, 20 μM Aβ25-35, 1 μM oAβ or 1 μM fAβ for 24 h. After incubation, cultured medium was collected to determine the level of IL-1β (black columns), TNF-α (striped columns) and NO (white columns). B. PAM and DPM were treated with vehicle, 20 ng/ml LPS or 5 ng/ml IFN-γ for 24 h. After incubation, cultured medium was collected to determine the level of IL-1β (black columns), TNF-α (striped columns) and NO (white columns). The results are the mean ± S.D. from six independent experiments. Significant differences between vehicle-treated cells and Aβ-treated cells are indicated by *, P < 0.05. Significant differences between PAM and DPM under the same treatments are indicated by #, P < 0.05.