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Table 1 Dopamine D 2 receptor mRNA ratios in SN and VTA of OVX+E 2 rats as determined by QRT-PCR

From: Involvement of dopamine D2 receptor in the diurnal changes of tuberoinfundibular dopaminergic neuron activity and prolactin secretion in female rats

  aCSF D2AODN D2random AODN
SN AM 1.00 ± 0.01 0.76 ± 0.06# 1.33 ± 0.13
PM 0.78 ± 0.02** 0.86 ± 0.03 0.99 ± 0.05*
VTA AM 1.02 ± 0.02 0.42 ± 0.02## 1.38 ± 0.19
PM 0.77 ± 0.01** 0.46 ± 0.06# 0.53 ± 0.08**
  1. Data are expressed as mean ± SEM (n = 8-12 rats in each group). *, p < 0.05; **, p < 0.01, compared with respective control groups in the morning; #, p < 0.05; ##, p < 0.01 compared with respective aCSF-treated groups at the same time point.
  2. Groups of OVX+E2 rats received icv injections of aCSF, antisense oligodeoxynucleotides (AODN, 10 μg/3 μl), or random AODN against D2 receptor mRNA for 2 days were sacrificed either in the morning or afternoon.