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Table 1 Dopamine D 2 receptor mRNA ratios in SN and VTA of OVX+E 2 rats as determined by QRT-PCR

From: Involvement of dopamine D2 receptor in the diurnal changes of tuberoinfundibular dopaminergic neuron activity and prolactin secretion in female rats

 

aCSF

D2AODN

D2random AODN

SN

AM

1.00 ± 0.01

0.76 ± 0.06#

1.33 ± 0.13

PM

0.78 ± 0.02**

0.86 ± 0.03

0.99 ± 0.05*

VTA

AM

1.02 ± 0.02

0.42 ± 0.02##

1.38 ± 0.19

PM

0.77 ± 0.01**

0.46 ± 0.06#

0.53 ± 0.08**

  1. Data are expressed as mean ± SEM (n = 8-12 rats in each group). *, p < 0.05; **, p < 0.01, compared with respective control groups in the morning; #, p < 0.05; ##, p < 0.01 compared with respective aCSF-treated groups at the same time point.
  2. Groups of OVX+E2 rats received icv injections of aCSF, antisense oligodeoxynucleotides (AODN, 10 μg/3 μl), or random AODN against D2 receptor mRNA for 2 days were sacrificed either in the morning or afternoon.
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Journal of Biomedical Science

ISSN: 1423-0127