Figure 4
From: Characterization of a new mouse p53 variant: loss-of-function and gain-of-function
The endogenous wild-type p53 level affects exogenous p53 functions. HeLa cells were transiently transfected with 0.03 μg (A) or 0.3 μg (B) pSG5.HA.p53 and the indicated amount of the new variant or R175H mutant p53 along with the pG13-LUC reporter gene (0.2 μg). The luciferase activities of the transfected cell extracts were determined. These data are the average of three experiments (mean ± S.D.; n = 3).