Figure 4

Noopept decreases the tau phosphorylation induced by Аβ in PC12 cells. Western blot analysis and graphs showed the changes in the content of the phosphorylated tau (Ser396) in PC12 cells pre-treated with noopept following by Аβ25–35 incubation. Densitometry values were normalized using the β-tubulin as internal control and expressed as means ± SEM. Four independent experiments were carried out using three replicate wells.