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Table 2 Type I error rate under the simulation scenario of no disease gene

From: Identifying rare and common disease associated variants in genomic data using Parkinson's disease as a model

Method GMSS CMC WSS SKAT-O
Type I error rate 0.04 0.05 0.08 0.06
  1. Data were generated for 5000 cases and 5000 controls based on a 1 MB region (5086 SNPs) of TGP sequencing data.