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Table 2 Type I error rate under the simulation scenario of no disease gene

From: Identifying rare and common disease associated variants in genomic data using Parkinson's disease as a model

Method

GMSS

CMC

WSS

SKAT-O

Type I error rate

0.04

0.05

0.08

0.06

  1. Data were generated for 5000 cases and 5000 controls based on a 1 MB region (5086 SNPs) of TGP sequencing data.
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Journal of Biomedical Science

ISSN: 1423-0127