Skip to main content

Table 7 Allele and haplotype association analysis for sigmoid colon cancer

From: Colorectal cancer susceptibility: apparent gender-related modulation by ABCB1 gene polymorphisms

M1a M2b M3c Case Control Case-Freq Control-Freq OR (95% C.I.) Chisq Pvalue
C - - 33.0 111.0 0.79 0.56 ref. d   
T - - 9.0 89.0 0.21 0.45 0.34 (0.15-0.75) 7.668 0.0056
- G - 32.0 108.0 0.73 0.54 ref.   
- T - 12.0 92.0 0.27 0.46 0.44 (0.21-0.90) 5.172 0.023
- - C 23.0 100.0 0.52 0.50 ref.   
- - T 21.0 100.0 0.48 0.50 0.91 (0.48-0.76) 0.075 0.78
C G - 30.0 97.4 0.71 0.49 ref. 7.104 0.0077
C T - 3.0 13.6 0.07 0.07 0.72 (0.19-2.68) 0.018 0.89
T G - 0.0 10.6 0.00 0.05 not calculable 2.237 0.13
T T - 9.0 78.4 0.21 0.39 0.37 (0.16-0.83) 4.916 0.027
C - C 22.0 91.0 0.52 0.48 ref. 0.277 0.60
C - T 11.0 16.0 0.26 0.08 2.84 (1.16-6.98) 10.560 0.0012
T - T 9.0 83.0 0.21 0.44 0.45 (0.20-1.03) 7.120 0.0076
- G C 21.9 90.3 0.50 0.45 ref. 0.328 0.57
- G T 10.1 17.7 0.23 0.09 2.37 (0.94-5.92) 7.129 0.0076
- T C 1.1 9.7 0.03 0.05 0.49 (0.06-4.09) 0.539 0.46
- T T 10.9 82.3 0.25 0.41 0.55 (0.25-1.20) 4.085 0.043
C G C 21.0 83.2 0.50 0.44 ref. 0.540 0.46
C G T 9.0 10.3 0.21 0.05 3.48 (1.23-9.82) 11.390 0.00074
C T C 1.0 7.8 0.02 0.04 0.51 (0.06-4.37) 0.289 0.59
C T T 2.0 5.7 0.05 0.03 1.38 (0.25-7.65) 0.488 0.49
T G T 0.0 7.6 0.00 0.04 not calculable 1.596 0.21
T T T 9.0 75.5 0.21 0.40 0.47 (0.20-1.10) 5.173 0.023
  1. aM1 1236 C > T rs1128503.
  2. bM2 2677 G > T/A rs2032582.
  3. cM3 3435 C > T rs1045642.
  4. dreference.