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Table 7 Allele and haplotype association analysis for sigmoid colon cancer

From: Colorectal cancer susceptibility: apparent gender-related modulation by ABCB1 gene polymorphisms

M1a

M2b

M3c

Case

Control

Case-Freq

Control-Freq

OR (95% C.I.)

Chisq

Pvalue

C

-

-

33.0

111.0

0.79

0.56

ref. d

  

T

-

-

9.0

89.0

0.21

0.45

0.34 (0.15-0.75)

7.668

0.0056

-

G

-

32.0

108.0

0.73

0.54

ref.

  

-

T

-

12.0

92.0

0.27

0.46

0.44 (0.21-0.90)

5.172

0.023

-

-

C

23.0

100.0

0.52

0.50

ref.

  

-

-

T

21.0

100.0

0.48

0.50

0.91 (0.48-0.76)

0.075

0.78

C

G

-

30.0

97.4

0.71

0.49

ref.

7.104

0.0077

C

T

-

3.0

13.6

0.07

0.07

0.72 (0.19-2.68)

0.018

0.89

T

G

-

0.0

10.6

0.00

0.05

not calculable

2.237

0.13

T

T

-

9.0

78.4

0.21

0.39

0.37 (0.16-0.83)

4.916

0.027

C

-

C

22.0

91.0

0.52

0.48

ref.

0.277

0.60

C

-

T

11.0

16.0

0.26

0.08

2.84 (1.16-6.98)

10.560

0.0012

T

-

T

9.0

83.0

0.21

0.44

0.45 (0.20-1.03)

7.120

0.0076

-

G

C

21.9

90.3

0.50

0.45

ref.

0.328

0.57

-

G

T

10.1

17.7

0.23

0.09

2.37 (0.94-5.92)

7.129

0.0076

-

T

C

1.1

9.7

0.03

0.05

0.49 (0.06-4.09)

0.539

0.46

-

T

T

10.9

82.3

0.25

0.41

0.55 (0.25-1.20)

4.085

0.043

C

G

C

21.0

83.2

0.50

0.44

ref.

0.540

0.46

C

G

T

9.0

10.3

0.21

0.05

3.48 (1.23-9.82)

11.390

0.00074

C

T

C

1.0

7.8

0.02

0.04

0.51 (0.06-4.37)

0.289

0.59

C

T

T

2.0

5.7

0.05

0.03

1.38 (0.25-7.65)

0.488

0.49

T

G

T

0.0

7.6

0.00

0.04

not calculable

1.596

0.21

T

T

T

9.0

75.5

0.21

0.40

0.47 (0.20-1.10)

5.173

0.023

  1. aM1 1236 C > T rs1128503.
  2. bM2 2677 G > T/A rs2032582.
  3. cM3 3435 C > T rs1045642.
  4. dreference.