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Figure 5 | Journal of Biomedical Science

Figure 5

From: Novel adjuvants from seaweed impede autophagy signaling in therapy-resistant residual pancreatic cancer

Figure 5

Seaweed polyphenol treatments regulate autophagy related (ATG3, ATG5, ATG12, LC3A, LC3B, Survivin ) protein expression in radiotherapy resistant residual PC tumors. (A) Images of TMAs labelled (automated IHC) for Blank (no primary antibody), hematoxylin-eosin, ATG3, ATG5, ATG12, LC3A, LC3B, and survivin. (B) Aperio TMA-quantitation analysis showing protein specific positivity magnitudes in mock-irradiated PC xenografts and residual PC tissues after clinical radiotherapy with or without SA-EA, PT-EA, or HT-EA treatment. Group-wise comparisons were made using Two-way ANOVA with Bonferroni’s post-hoc correction.

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