Figure 5

SHP increases PPARγ2 expression in primary hepatocytes. Expression of SHP, CYP7A1 and PPARγ2 in adenovirus-mediated GFP- or SHP-overexpressing hepatocytes by real-time quantitative PCR analysis. Hepatocytes were infected with green fluorescent protein (GFP) or SHP adenovirus as indicated. Data are expressed as relative fold change after normalized to 36B4 and are mean ± SEM (n = 4–5 per group). *P < 0.001, **P < 0.05, compared with GFP-infected cells.