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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: Antitumoral effects of cyclin-dependent kinases inhibitors CR8 and MR4 on chronic myeloid leukemia cell lines

Fig. 5

Involvement of caspases processing in CDKs inhibitors-induced apoptosis in KCL22 cells. a Cells were left untreated or treated with Imatinib or Roscovitine (10 μM), or R-CR8 (0.1, 1 or 10 μM) before detection of cleaved caspase 3 by flow cytometry. b KCL22 cellular extracts were analyzed for caspase 3 and PARP cleavage after 10 μM treatment by drugs. Actin was used as a control of sample loading. No T not treated, Imat Imatinib, Rosc Roscovitine

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Journal of Biomedical Science

ISSN: 1423-0127