Table 2 Genotype distribution of CDH13 and APN SNPs with respect to CRC in KCP-II
From: Gene-gene interaction analysis identifies a new genetic risk factor for colorectal cancer
Gene | SNP | Group (n) | Genotype | p-value | ||
|---|---|---|---|---|---|---|
Frequency | ||||||
CDH13 | rs3865188 | Â | AA | AT | TT | Â |
Case (325) | 0.4646 | 0.3815 | 0.1538 | 0.0474 * | ||
Control (977) | 0.4862 | 0.4104 | 0.1034 | |||
APN | rs182052 | Â | AA | AG | GG | Â |
Case (325) | 0.2646 | 0.5077 | 0.2277 | 0.4161 | ||
Control (974) | 0.2402 | 0.4979 | 0.2618 | |||
rs1736656 | Â | AA | AG | GG | Â | |
Case(325) | 0.0000 | 0.5540 | 0.9446 | 0.4235 | ||
Control (977) | 0.0100 | 0.3990 | 0.9591 | |||
rs2241767 | Â | AA | AG | GG | Â | |
Case (325) | 0.4954 | 0.4246 | 0.0800 | 0.7045 | ||
Control (977) | 0.5067 | 0.4023 | 0.0811 | |||
rs3821799 | Â | CC | CT | TT | Â | |
Case (325) | 0.1692 | 0.4677 | 0.3631 | 0.3357 | ||
Control (968) | 0.1395 | 0.4638 | 0.3967 | |||
rs3774261 | Â | AA | AG | GG | Â | |
Case (324) | 0.3179 | 0.5062 | 0.1759 | 0.1516 | ||
Control (972) | 0.3755 | 0.4743 | 0.1502 | |||
rs6773957 | Â | AA | AG | GG | Â | |
Case (325) | 0.3169 | 0.5046 | 0.1785 | 0.1417 | ||
Control (977) | 0.3756 | 0.4719 | 0.1525 | |||