Fig. 7

Mechanism of caffeic acid ethanolamide (CAEA) affecting cardiac oxidative stress and cardiac bioenergetics in mice subjected to two weeks subcutaneous isoproterenol (ISO) injections. a Quantification of cardiac sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) activity. b Quantification of cardiac lipid peroxidation. c Representative Western blot image of cardiac HIF-1α expression. d Densitometry of cardiac HIF-1α expression. e Quantification of cardiac lactate content. f Representative M-mode echocardiogram. g Quantification of left ventricular ejection fraction. h Quantification of cardiac ATP content. n = 6 ~ 9, **P <0.01 versus control, *P <0.05 versus control, ^# P <0.05 versus ISO, ^@ P <0.05 versus ISO + CAEA. (Nic = nicotinamide)