Table 2 The effect of aging on hematological parameters and systemic cytokines profile

Cell Blood Count (CBC)

 Red blood cell number (10⁶/ mm³)

4.4 ± 1

7.3 ± 0.2^#

7.0 ± 0.3^#

 White blood cell number (10³/ mm³)

2.9 ± 0.4

2.8 ± 0.3

5.3 ± 1

 Myeloid (%)

24 ± 4.3

27 ± 4.1

40 ± 4.2*

 Lymphoid (%)

76 ± 4.3

73 ± 4.1

60 ± 4.2*

Myeloid Cytokines (pg/mL)

 IL-6

256 ± 30

348 ± 34

543 ± 37*

 TNF

265 ± 19

398 ± 17

588 ± 80*

 IL-12

153 ± 12

187 ± 8

172 ± 16

Lymphoid Cytokines (pg/mL)

 IFN-γ

69 ± 1.5

77 ± 2.3

75 ± 3.3

 IL-10

516 ± 34

586 ± 22

573 ± 19