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Table 2 The effect of aging on hematological parameters and systemic cytokines profile

From: Reactive oxygen species contribute to dysfunction of bone marrow hematopoietic stem cells in aged C57BL/6 J mice

Parameters Groups
Young Middle Aged
Cell Blood Count (CBC)    
 Red blood cell number (106/ mm3) 4.4 ± 1 7.3 ± 0.2# 7.0 ± 0.3#
 White blood cell number (103/ mm3) 2.9 ± 0.4 2.8 ± 0.3 5.3 ± 1
 Myeloid (%) 24 ± 4.3 27 ± 4.1 40 ± 4.2*
 Lymphoid (%) 76 ± 4.3 73 ± 4.1 60 ± 4.2*
Myeloid Cytokines (pg/mL)    
 IL-6 256 ± 30 348 ± 34 543 ± 37*
 TNF 265 ± 19 398 ± 17 588 ± 80*
 IL-12 153 ± 12 187 ± 8 172 ± 16
Lymphoid Cytokines (pg/mL)    
 IFN-γ 69 ± 1.5 77 ± 2.3 75 ± 3.3
 IL-10 516 ± 34 586 ± 22 573 ± 19
  1. Values are means ± SEM for six to 11 animals per group. *p < 0.05 vs young and middle age; #p < 0.05 vs young (one-way ANOVA)