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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: Soluble epoxide hydrolase inhibitor enhances synaptic neurotransmission and plasticity in mouse prefrontal cortex

Fig. 5

sEH inhibitor, AUDA, facilitates LTP in PFC slice. a The graph represents the mean ± SEM slope of fEPSPs plotted against time. Applied with 3× high-frequency stimulation of 100 Hz for 1 s induced LTP. b In the presence of 1 μM AUDA, the enhancement of LTP was observed. c Comparison of fEPSPs slope potentiation 10 min after tetanus in the absence or presence AUDA is shown. d Comparison of fEPSPs slope potentiation 60 min after tetanus in the absence or presence AUDA is shown. **p < 0.01 vs. vehicle control

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Journal of Biomedical Science

ISSN: 1423-0127