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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Significance of the urokinase-type plasminogen activator and its receptor in the progression of focal segmental glomerulosclerosis in clinical and mouse models

Fig. 4

Urokinase-type plasminogen activator (uPA)-deficient mice failed to generate a type 2 immune response in a focal segmental glomerulosclerosis (FSGS) mouse model. Plasma samples in the wild-type (WT) and uPA−/− groups were collected at indicated time points to determine levels of immunoglobulin G1 (IgG1), IgG2a, and IgG3. Data are presented as the ratio of IgG1 over the combination of IgG2a and IgG3. # p < 0.05 vs. week 0 (W0); *p < 0.05 vs. the WT

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