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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: CD44-mediated monocyte transmigration across Cryptococcus neoformans-infected brain microvascular endothelial cells is enhanced by HIV-1 gp41-I90 ectodomain

Fig. 2

Cn and HIV-1 gp41-I90 induce THP-1 transmigration across HBMEC monolayers in a dose- and time-dependent manner. a, c Different doses (106-2 × 107 CFU/ml) of Cn and HIV-1 gp41-I90 (0–20 μM) induced THP-1 transmigration. b, d Time-course study of Cn and HIV-1 gp41-I90-induced THP-1 transmigration across HBMEC monolayers. THP-1 transmigration was triggered by 5 × 106 CFU/ml of Cn or 2 μM HIV-1 gp41-I90. The values represent the mean percent transmigrating THP-1 of triplicate samples and are representative of one experiment from three independent experiments showing similar data. *P < 0.05, **P <0.01, ***P < 0.001 compared with control

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Journal of Biomedical Science

ISSN: 1423-0127