Fig. 3
From: The genetics and screening of familial hypercholesterolaemia
ApoB gene. a. Location of the ApoB gene on the short (p) arm of chromosome 2 between positions 24 and 23. b. Numbered vertical bars representing the exons. c. Only 8 disease-associated sequence variants have been found to occur in ApoB, and the majority of these are at the mutational hotspot exon 26. When translated this domain functions as the region for LDLR binding. Data extracted from [23–25]