Table 2 Immunocytochemistry profile of TOP2A and Ki-67 antibodies related to cytopathology classification of cervical smears
Cytopathology | N | HPV+ (%) | Immunocytochemistry | |||
|---|---|---|---|---|---|---|
TOP2A+ (%) | Ki-67+ (%) | TOP2A+/Ki-67+ (%) | ICC+ (%) | |||
Positive | 32*,**,***,**** | 28 (87.5) | 23* (71.9) | 26** (81.2) | 19*** (59.4) | 30**** (93.7) |
ASC-US | 5 | 3 (60) | 2 (40) | 3 (60) | 1 (20) | 4 (80) |
LSIL | 19 | 18 (94.7) | 13 (68) | 16 (84) | 11 (57.9) | 18 (94.7) |
HSIL | 8 | 7 (87.5) | 8 (100) | 7 (87.5) | 7 (87.5) | 8 (100) |
NILM | 78 | 55 (70.5) | 28 (36) | 21 (27) | 18 (23) | 31 (39.7) |
Total | 110 | 83 | 51 | 47 | 37 | 61 |