Fig. 9

Sonograms and Doppler imaging of developed xenografts in vivo. The longitudinal cross-section images (a, c) were acquired from malignant xenografts. The transverse cross-section images (b, d) were acquired from the benign xenografts. The color Doppler imaging (c, d) quantifies the vascular flow velocity around the xenograft and surrounding region by pseudo colors. The green cursers indicate corresponding xenograft lengths, 0.76 cm in (a) and 1.18 cm in (b). The morphology of malignant xenograft (MCF-7 xenograft) was demonstrated in (a) with angular/ill-defined margin (orange arrows)