Fig. 3

Successful delivery of siRNA into hippocampal CA1 subfield. Fluorescent double staining of FITC-siRNA (green) and DAPI (blue) were observed in the hippocampal CA1 subfield 24 h after injection of 400 nl FITC-siRNA (10 μM), which was distributed in the cytosol of hippocampal CA1 in both sham-control (a) and in the rats subjected to TGI-reperfusion for 4 h (b). Scale bar: 10 μm. I/R: ischemia/reperfusion